What is the most commonly used screen reader and browser combination (as of 2021)?
JAWS with Chrome
According to a 2021 WebAIM survey, 32.5% of screen reader user respondents used JAWS with Chrome. NVDA with Chrome, the second most popular combination, represented 16% of respondent users. VoiceOver with Safari represented 4.7% of respondents, while NVDA with Firefox represented 9.7%.